The physiologic changes that occur with advancing age and their effect on the duration of peripheral nerve blocks have yet to be defined. We prospectively studied the duration of sciatic nerve block using mepivacaine in younger and older patients. Eighty ASA physical status I-III patients, aged 18-35 (n = 40) or 55-80 (n = 40) [...]

Pharmaceutical outsourcing project name:: Aminoglutethimide Tablets
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Pharmaceutical outsourcing project English name: AMINOGLUTETHIMIDE TABLETS
Pharmaceutical outsourcing project categories: hormones and anti-hormone anti-tumor
Pharmacokinetics: healthy adults after oral administration of 500mg of the product 1.5 hours, with an average maximum plasma concentration of 5.9μg/ml, the average plasma half-life of 12.5 hours, [...]